• Cervical Cancer

    Even with an annual Pap smear test and the new vaccination for young women, cervical cancer can’t be totally prevented. But there are some things you can do to reduce your risk of developing cancer of the cervix.

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  • Vaginal Cancer

    Vaginal cancer is a relatively rare disorder, comprising about 2% to 3% of all gynecologic cancers. Approximately 2,400 women are diagnosed each year with vaginal cancer in the United States.

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  • Ovarian Cancer

    The chance of getting ovarian cancer increases as a woman gets older. Ovarian cancer occurs in women over the age of 50 and the highest risk is in women over 60.

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  • Uterine/Endometrial Cancer

    Uterine cancer is the most common of all cancers in the female reproductive system. It can either form in the inner lining of the uterus or the outer layer of muscle tissue.

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  • Molar Pregnancy

    Thought to be caused by a problem with the genetic information transmitted between an egg and sperm, molar pregnancy can develop during the first trimester of pregnancy.

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Testimonials

  • Jan Holsclaw

    When Jan Holsclaw found out she had ovarian cancer, she was referred to Dr. Bigsby at Florida Hospital Cancer Institute for surgery and treatment. With reassuring words and...

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  • Picture 4_0_0.png
    Jan C. Garavaglia, M.D., (aka "Dr. G")
    TV Personality Jan C. Garavaglia, M.D., (aka "Dr. G") is the chief medical examiner for the District Nine (Orange-Osceola) Medical Examiner's Office in Florida.  When she...
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  • Bonnie Donihi

    Bonnie has helped to raise millions of dollars for ovarian cancer research taking place at National Cancer Institute (NCI), Department of Defense (DOD), Centers for Disease...

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Uterine Cancer Research

Research is being conducted worldwide by some of the most highly regarded experts in the field. As promising treatments come to the forefront, patients have the opportunity to participate in carefully controlled research studies known as clinical trials. These studies allow you to be on the cutting edge of treatment for uterine cancer, gaining access to protocols that may not be available to the general public for months, if not years.

Molecular Pathology of Endometrial Cancer

One of the keys to finding an eventual cure of uterine cancer is to understand how normal cells become cancerous. For years it has been known that damaged or defective DNA can mutate, altering important genes that regular cell growth. It the genes are damaged, growth can go unchecked and cancer can result.

Researchers are currently looking at ways to identify damaged or defective DNA in the genes and repair them, preventing endometrial cancer from forming. Tests may also be able to predict how aggressive a cancer may be so the treatment can be configured to address the aggressiveness head on with the right dosages or responses.

Tumor Markers

Certain molecules that are released by cancer cells can help doctors detect the recurrence of some forms of cancer. CA 125 is an example. This molecule is a marker that is used to find recurrent forms of ovarian cancer. Blood tests for CA 125 may also be able to identify the presence of recurrent endometrial cancer, even before it can be seen in a CAT Scan or MRI. Tumor markers may someday allow doctors to decide which patients will benefit most from surgery versus other treatment options.

New Treatments

Researchers are also investigating a number of new drugs, drug combinations and “targeted therapies” for patients with advanced stages of endometrial cancer. The use of adjuvant chemotherapy, either with or without radiation therapy is also being studied.

Currently, the National Cancer Institute lists nearly 129 clinical trials underway for the most common form of uterine cancer, endometrial cancer, and 71 trials for uterine secoma.

For a complete list, click here.